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Nanochannel Electroporation as a Platform for Living Cell Interrogation in Acute Myeloid Leukemia
A living cell interrogation platform based on nanochannel electroporation is demonstrated with analysis of RNAs in single cells. This minimally invasive process is based on individual cells and allows both multi‐target analysis and stimulus‐response analysis by sequential deliveries. The unique plat...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5115302/ https://www.ncbi.nlm.nih.gov/pubmed/27980918 http://dx.doi.org/10.1002/advs.201500111 |
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author | Zhao, Xi Huang, Xiaomeng Wang, Xinmei Wu, Yun Eisfeld, Ann‐Kathrin Schwind, Sebastian Gallego‐Perez, Daniel Boukany, Pouyan E. Marcucci, Guido I. Lee, Ly James |
author_facet | Zhao, Xi Huang, Xiaomeng Wang, Xinmei Wu, Yun Eisfeld, Ann‐Kathrin Schwind, Sebastian Gallego‐Perez, Daniel Boukany, Pouyan E. Marcucci, Guido I. Lee, Ly James |
author_sort | Zhao, Xi |
collection | PubMed |
description | A living cell interrogation platform based on nanochannel electroporation is demonstrated with analysis of RNAs in single cells. This minimally invasive process is based on individual cells and allows both multi‐target analysis and stimulus‐response analysis by sequential deliveries. The unique platform possesses a great potential to the comprehensive and lysis‐free nucleic acid analysis on rare or hard‐to‐transfect cells. [Image: see text] |
format | Online Article Text |
id | pubmed-5115302 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2015 |
publisher | John Wiley and Sons Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-51153022016-12-15 Nanochannel Electroporation as a Platform for Living Cell Interrogation in Acute Myeloid Leukemia Zhao, Xi Huang, Xiaomeng Wang, Xinmei Wu, Yun Eisfeld, Ann‐Kathrin Schwind, Sebastian Gallego‐Perez, Daniel Boukany, Pouyan E. Marcucci, Guido I. Lee, Ly James Adv Sci (Weinh) Communications A living cell interrogation platform based on nanochannel electroporation is demonstrated with analysis of RNAs in single cells. This minimally invasive process is based on individual cells and allows both multi‐target analysis and stimulus‐response analysis by sequential deliveries. The unique platform possesses a great potential to the comprehensive and lysis‐free nucleic acid analysis on rare or hard‐to‐transfect cells. [Image: see text] John Wiley and Sons Inc. 2015-07-16 /pmc/articles/PMC5115302/ /pubmed/27980918 http://dx.doi.org/10.1002/advs.201500111 Text en © 2015 The Authors. Published by WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim This is an open access article under the terms of the Creative Commons Attribution (http://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Communications Zhao, Xi Huang, Xiaomeng Wang, Xinmei Wu, Yun Eisfeld, Ann‐Kathrin Schwind, Sebastian Gallego‐Perez, Daniel Boukany, Pouyan E. Marcucci, Guido I. Lee, Ly James Nanochannel Electroporation as a Platform for Living Cell Interrogation in Acute Myeloid Leukemia |
title | Nanochannel Electroporation as a Platform for Living Cell Interrogation in Acute Myeloid Leukemia |
title_full | Nanochannel Electroporation as a Platform for Living Cell Interrogation in Acute Myeloid Leukemia |
title_fullStr | Nanochannel Electroporation as a Platform for Living Cell Interrogation in Acute Myeloid Leukemia |
title_full_unstemmed | Nanochannel Electroporation as a Platform for Living Cell Interrogation in Acute Myeloid Leukemia |
title_short | Nanochannel Electroporation as a Platform for Living Cell Interrogation in Acute Myeloid Leukemia |
title_sort | nanochannel electroporation as a platform for living cell interrogation in acute myeloid leukemia |
topic | Communications |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5115302/ https://www.ncbi.nlm.nih.gov/pubmed/27980918 http://dx.doi.org/10.1002/advs.201500111 |
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