Cancer Therapy: Anti‐Metastatic and Anti‐Angiogenic Activities of Core–Shell SiO(2)@LDH Loaded with Etoposide in Non‐Small Cell Lung Cancer (Adv. Sci. 11/2016)

In article 1600229, Shilong Wang, Rongrong Zhu, Yechang Qian, and co‐workers investigate the anti‐metastatic and anti‐angiogenic effects of SiO(2)@LDH (LDH: layered double hydroxide) loaded with etoposide (VP16). SiO(2)@LDH has very suitable qualities as drug delivery agent and enhances the anti‐met...

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Detalles Bibliográficos
Autores principales: Zhu, Yanjing, Zhu, Rongrong, Wang, Mei, Wu, Bin, He, Xiaolie, Qian, Yechang, Wang, Shilong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Cover Picture
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5115527/
http://dx.doi.org/10.1002/advs.201670056
Descripción
Sumario:In article 1600229, Shilong Wang, Rongrong Zhu, Yechang Qian, and co‐workers investigate the anti‐metastatic and anti‐angiogenic effects of SiO(2)@LDH (LDH: layered double hydroxide) loaded with etoposide (VP16). SiO(2)@LDH has very suitable qualities as drug delivery agent and enhances the anti‐metastatic action of VP16 both in vitro and in vivo. Enhanced anti‐angiogenic efficacy is also proven which might contribute to the anti‐cancer action. The cover image represents the 3D structure of core‐shell SiO(2)@LDH‐VP16, which silicon dioxide sphere flexibly enclosed by double‐layered hydroxide. [Image: see text]

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