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Cyclooxygenase Isoform Exchange Blocks Brain-Mediated Inflammatory Symptoms
Cyclooxygenase-2 (COX-2) is the main source of inducible prostaglandin E(2) production and mediates inflammatory symptoms including fever, loss of appetite and hyperalgesia. COX-1 is dispensable for fever, anorexia and hyperalgesia but is important for several other functions both under basal condit...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5115700/ https://www.ncbi.nlm.nih.gov/pubmed/27861574 http://dx.doi.org/10.1371/journal.pone.0166153 |