A Rapid-Response Humoral Vaccine Platform Exploiting Pre-Existing Non-Cognate Populations of Anti-Vaccine or Anti-Viral CD4+ T Helper Cells to Confirm B Cell Activation

The need for CD4+ T cell responses to arise de novo following vaccination can limit the speed of B cell responses. Populations of pre-existing vaccine-induced or anti-viral CD4+ T cells recognising distinct antigens could be exploited to overcome this limitation. We hypothesise that liposomal vaccin...

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Detalles Bibliográficos
Autores principales: Hills, Thomas, Jakeman, Phillip G., Carlisle, Robert C., Klenerman, Paul, Seymour, Leonard W., Cawood, Ryan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5115735/
https://www.ncbi.nlm.nih.gov/pubmed/27861512
http://dx.doi.org/10.1371/journal.pone.0166383

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