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On the Ribosomal Density that Maximizes Protein Translation Rate

During mRNA translation, several ribosomes attach to the same mRNA molecule simultaneously translating it into a protein. This pipelining increases the protein translation rate. A natural and important question is what ribosomal density maximizes the protein translation rate. Using mathematical mode...

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Detalles Bibliográficos
Autores principales: Zarai, Yoram, Margaliot, Michael, Tuller, Tamir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5115748/
https://www.ncbi.nlm.nih.gov/pubmed/27861564
http://dx.doi.org/10.1371/journal.pone.0166481