Cargando…
Molecular Characterization of Striated Muscle-Specific Gab1 Isoform as a Critical Signal Transducer for Neuregulin-1/ErbB Signaling in Cardiomyocytes
Grb2-associated binder (Gab) docking proteins regulate signals downstream of a variety of growth factors and receptor tyrosine kinases. Neuregulin-1 (NRG-1), a member of epidermal growth factor family, plays a critical role for cardiomyocyte proliferation and prevention of heart failure via ErbB rec...
Autores principales: | Yasui, Taku, Masaki, Takeshi, Arita, Yoh, Ishibashi, Tomohiko, Inagaki, Tadakatsu, Okazawa, Makoto, Oka, Toru, Shioyama, Wataru, Yamauchi-Takihara, Keiko, Komuro, Issei, Sakata, Yasushi, Nakaoka, Yoshikazu |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5115770/ https://www.ncbi.nlm.nih.gov/pubmed/27861634 http://dx.doi.org/10.1371/journal.pone.0166710 |
Ejemplares similares
-
On the Modulatory Roles of Neuregulins/ErbB Signaling on Synaptic Plasticity
por: Ledonne, Ada, et al.
Publicado: (2019) -
Gab Docking Proteins in Cardiovascular Disease, Cancer, and Inflammation
por: Nakaoka, Yoshikazu, et al.
Publicado: (2013) -
Neuregulin-1-mediated ErbB2–ErbB3 signalling protects human trophoblasts against apoptosis to preserve differentiation
por: Fock, Valerie, et al.
Publicado: (2015) -
Dysregulation of Neuregulin-1/ErbB signaling in the hippocampus of rats after administration of doxorubicin
por: Liao, Dehua, et al.
Publicado: (2018) -
Interactions among genes in the ErbB-Neuregulin signalling network are associated with increased susceptibility to schizophrenia
por: Benzel, Isabel, et al.
Publicado: (2007)