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A Genetic Algorithm for Diploid Genome Reconstruction Using Paired-End Sequencing
The genome of many species in the biosphere is a diploid consisting of paternal and maternal haplotypes. The differences between these two haplotypes range from single nucleotide polymorphisms (SNPs) to large-scale structural variations (SVs). Existing genome assemblers for next-generation sequencin...
Autores principales: | Ting, Chuan-Kang, Lin, Choun-Sea, Chan, Ming-Tsai, Chen, Jian-Wei, Chuang, Sheng-Yu, Huang, Yao-Ting |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5115803/ https://www.ncbi.nlm.nih.gov/pubmed/27861560 http://dx.doi.org/10.1371/journal.pone.0166721 |
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