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Automated structure refinement of macromolecular assemblies from cryo-EM maps using Rosetta

Cryo-EM has revealed the structures of many challenging yet exciting macromolecular assemblies at near-atomic resolution (3–4.5Å), providing biological phenomena with molecular descriptions. However, at these resolutions, accurately positioning individual atoms remains challenging and error-prone. M...

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Detalles Bibliográficos
Autores principales: Wang, Ray Yu-Ruei, Song, Yifan, Barad, Benjamin A, Cheng, Yifan, Fraser, James S, DiMaio, Frank
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5115868/
https://www.ncbi.nlm.nih.gov/pubmed/27669148
http://dx.doi.org/10.7554/eLife.17219