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Haploinsufficiency of the Myc regulator Mtbp extends survival and delays tumor development in aging mice
Alterations of specific genes can modulate aging. Myc, a transcription factor that regulates the expression of many genes involved in critical cellular functions was shown to have a role in controlling longevity. Decreased expression of Myc inhibited many of the deleterious effects of aging and incr...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Impact Journals LLC
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5115908/ https://www.ncbi.nlm.nih.gov/pubmed/27803394 http://dx.doi.org/10.18632/aging.101092 |