Structure of the NS2B-NS3 protease from Zika virus after self-cleavage

The recent outbreak of Zika virus (ZIKV) infections in the Americas represents a serious threat to the global public health. The viral protease that processes viral polyproteins during infection appears as an attractive drug target. Here we report a crystal structure at 1.84 Å resolution of ZIKV non...

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Detalles Bibliográficos
Autores principales: Phoo, Wint Wint, Li, Yan, Zhang, Zhenzhen, Lee, Michelle Yueqi, Loh, Ying Ru, Tan, Yaw Bia, Ng, Elizabeth Yihui, Lescar, Julien, Kang, CongBao, Luo, Dahai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5116066/
https://www.ncbi.nlm.nih.gov/pubmed/27845325
http://dx.doi.org/10.1038/ncomms13410

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