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In silico Pathway Activation Network Decomposition Analysis (iPANDA) as a method for biomarker development

Signalling pathway activation analysis is a powerful approach for extracting biologically relevant features from large-scale transcriptomic and proteomic data. However, modern pathway-based methods often fail to provide stable pathway signatures of a specific phenotype or reliable disease biomarkers...

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Detalles Bibliográficos
Autores principales:	Ozerov, Ivan V., Lezhnina, Ksenia V., Izumchenko, Evgeny, Artemov, Artem V., Medintsev, Sergey, Vanhaelen, Quentin, Aliper, Alexander, Vijg, Jan, Osipov, Andreyan N., Labat, Ivan, West, Michael D., Buzdin, Anton, Cantor, Charles R., Nikolsky, Yuri, Borisov, Nikolay, Irincheeva, Irina, Khokhlovich, Edward, Sidransky, David, Camargo, Miguel Luiz, Zhavoronkov, Alex
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5116087/ https://www.ncbi.nlm.nih.gov/pubmed/27848968 http://dx.doi.org/10.1038/ncomms13427

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