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TET-dependent regulation of retrotransposable elements in mouse embryonic stem cells

BACKGROUND: Ten-eleven translocation (TET) enzymes oxidise DNA methylation as part of an active demethylation pathway. Despite extensive research into the role of TETs in genome regulation, little is known about their effect on transposable elements (TEs), which make up nearly half of the mouse and...

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Detalles Bibliográficos
Autores principales:	de la Rica, Lorenzo, Deniz, Özgen, Cheng, Kevin C. L., Todd, Christopher D., Cruz, Cristina, Houseley, Jonathan, Branco, Miguel R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2016
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5116139/ https://www.ncbi.nlm.nih.gov/pubmed/27863519 http://dx.doi.org/10.1186/s13059-016-1096-8

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