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In epithelial cancers, aberrant COL17A1 promoter methylation predicts its misexpression and increased invasion

BACKGROUND: Metastasis is a leading cause of death among cancer patients. In the tumor microenvironment, altered levels of extracellular matrix proteins, such as collagens, can facilitate the first steps of cancer cell metastasis, including invasion into surrounding tissue and intravasation into the...

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Detalles Bibliográficos
Autores principales: Thangavelu, Pulari U., Krenács, Tibor, Dray, Eloise, Duijf, Pascal H. G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5116176/
https://www.ncbi.nlm.nih.gov/pubmed/27891193
http://dx.doi.org/10.1186/s13148-016-0290-6