Defective autophagy leads to the suppression of stem-like features of CD271(+) osteosarcoma cells

BACKGROUND: As an important stress-response mechanism, autophagy plays crucial role in the tumor formation and drug resistance of cancer cells including osteosarcoma (OS). OS cancer stem cells (CSCs) also are considered a key factor of tumorigenesis, drug resistance and tumor recurrence. However, th...

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Detalles Bibliográficos
Autores principales: Zhang, Dong, Zhao, Qing, Sun, Hao, Yin, Lijuan, Wu, Jiajun, Xu, Jun, He, Tianxiang, Yang, Chunlei, Liang, Chengwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5116184/
https://www.ncbi.nlm.nih.gov/pubmed/27863492
http://dx.doi.org/10.1186/s12929-016-0297-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5116184/
https://www.ncbi.nlm.nih.gov/pubmed/27863492
http://dx.doi.org/10.1186/s12929-016-0297-5

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