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Rheumatoid synovial fibroblasts differentiate into distinct subsets in the presence of cytokines and cartilage
BACKGROUND: We investigated two distinct synovial fibroblast populations that were located preferentially in the lining or sub-lining layers and defined by their expression of either podoplanin (PDPN) or CD248, and explored their ability to undergo self-assembly and transmigration in vivo. METHODS:...
Autores principales: | , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5116193/ https://www.ncbi.nlm.nih.gov/pubmed/27863512 http://dx.doi.org/10.1186/s13075-016-1156-1 |