Rheumatoid synovial fibroblasts differentiate into distinct subsets in the presence of cytokines and cartilage

BACKGROUND: We investigated two distinct synovial fibroblast populations that were located preferentially in the lining or sub-lining layers and defined by their expression of either podoplanin (PDPN) or CD248, and explored their ability to undergo self-assembly and transmigration in vivo. METHODS:...

Descripción completa

Detalles Bibliográficos
Autores principales: Croft, Adam P., Naylor, Amy J., Marshall, Jennifer L., Hardie, Debbie L., Zimmermann, Birgit, Turner, Jason, Desanti, Guillaume, Adams, Holly, Yemm, Adrian I., Müller-Ladner, Ulf, Dayer, Jean-Michel, Neumann, Elena, Filer, Andrew, Buckley, Christopher D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5116193/
https://www.ncbi.nlm.nih.gov/pubmed/27863512
http://dx.doi.org/10.1186/s13075-016-1156-1

Ejemplares similares

Ejemplares similares