Transgenic mice overexpressing the ALS-linked protein Matrin 3 develop a profound muscle phenotype

Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disorder of upper and lower motor neurons. Mutations in the gene encoding the nuclear matrix protein Matrin 3 have been found in familial cases of ALS, as well as autosomal dominant distal myopathy with vocal cord and pharyngeal...

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Detalles Bibliográficos
Autores principales: Moloney, Christina, Rayaprolu, Sruti, Howard, John, Fromholt, Susan, Brown, Hilda, Collins, Matt, Cabrera, Mariela, Duffy, Colin, Siemienski, Zoe, Miller, Dave, Swanson, Maurice S., Notterpek, Lucia, Borchelt, David R., Lewis, Jada
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5116203/
https://www.ncbi.nlm.nih.gov/pubmed/27863507
http://dx.doi.org/10.1186/s40478-016-0393-5

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