Next-generation sequencing facilitates detection of the classic E13-A20 EML4-ALK fusion in an ALK-FISH/IHC inconclusive biopsy of a stage IV lung cancer patient: a case report

BACKGROUND: Inhibition of the oncogenic fusion-gene EML4-ALK is a current first-line approach for patients with stage IV non-small cell lung cancer. While FISH was established as the gold standard for identifying these patients, there is accumulating evidence that other methods of detection, i.e., i...

Descripción completa

Detalles Bibliográficos
Autores principales: Volckmar, Anna-Lena, Endris, Volker, Bozorgmehr, Farastuk, Lier, Clemens, Porcel, Carlota, Kirchner, Martina, Leichsenring, Jonas, Penzel, Roland, Thomas, Michael, Schirmacher, Peter, Warth, Arne, Stenzinger, Albrecht
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5116222/
https://www.ncbi.nlm.nih.gov/pubmed/27863497
http://dx.doi.org/10.1186/s13000-016-0581-4

Ejemplares similares

Ejemplares similares