Cargando…
Clearing the corpses: regulatory mechanisms, novel tools, and therapeutic potential of harnessing microglial phagocytosis in the diseased brain
Apoptosis is a widespread phenomenon that occurs in the brain in both physiological and pathological conditions. Dead cells must be quickly removed to avoid the further toxic effects they exert in the parenchyma, a process executed by microglia, the brain professional phagocytes. Although phagocytos...
Autores principales: | Diaz-Aparicio, Irune, Beccari, Sol, Abiega, Oihane, Sierra, Amanda |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Medknow Publications & Media Pvt Ltd
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5116820/ https://www.ncbi.nlm.nih.gov/pubmed/27904472 http://dx.doi.org/10.4103/1673-5374.193220 |
Ejemplares similares
-
Microglial phagocytosis dysfunction in the dentate gyrus is related to local neuronal activity in a genetic model of epilepsy
por: Sierra‐Torre, Virginia, et al.
Publicado: (2020) -
Janus-faced microglia: beneficial and detrimental consequences of microglial phagocytosis
por: Sierra, Amanda, et al.
Publicado: (2013) -
Surveillance, Phagocytosis, and Inflammation: How Never-Resting Microglia Influence Adult Hippocampal Neurogenesis
por: Sierra, Amanda, et al.
Publicado: (2014) -
Neuronal Hyperactivity Disturbs ATP Microgradients, Impairs Microglial Motility, and Reduces Phagocytic Receptor Expression Triggering Apoptosis/Microglial Phagocytosis Uncoupling
por: Abiega, Oihane, et al.
Publicado: (2016) -
Correction: Neuronal Hyperactivity Disturbs ATP Microgradients, Impairs Microglial Motility, and Reduces Phagocytic Receptor Expression Triggering Apoptosis/Microglial Phagocytosis Uncoupling
por: Abiega, Oihane, et al.
Publicado: (2016)