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Ankle to brachial systolic pressure index at rest increases with age in asymptomatic physically active participants

BACKGROUND: It is commonly acknowledged that the ability to use the ankle–brachial index (ABI), a reliable way to diagnose atherosclerosis, decreases with age in the general population. The aim of this study was to determine the relationship between resting ABI and age in different populations. METH...

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Autores principales: Congnard, Florian, Abraham, Pierre, Vincent, François, Le tourneau, Thierry, Carre, François, Hupin, David, Hamel, Jean François, Vielle, Bruno, Bruneau, Antoine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5117022/
https://www.ncbi.nlm.nih.gov/pubmed/27900144
http://dx.doi.org/10.1136/bmjsem-2015-000081
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author Congnard, Florian
Abraham, Pierre
Vincent, François
Le tourneau, Thierry
Carre, François
Hupin, David
Hamel, Jean François
Vielle, Bruno
Bruneau, Antoine
author_facet Congnard, Florian
Abraham, Pierre
Vincent, François
Le tourneau, Thierry
Carre, François
Hupin, David
Hamel, Jean François
Vielle, Bruno
Bruneau, Antoine
author_sort Congnard, Florian
collection PubMed
description BACKGROUND: It is commonly acknowledged that the ability to use the ankle–brachial index (ABI), a reliable way to diagnose atherosclerosis, decreases with age in the general population. The aim of this study was to determine the relationship between resting ABI and age in different populations. METHODS: 674 physically active participants with (active high risk, ACT(HR)) or without (active low risk, ACT(LR)) cardiovascular risk factors or/and sedentary (SED) subjects, aged 20–70 years. Systolic arterial pressure was recorded at rest and simultaneously with automatic sphygmomanometers at the arms and ankles. ABI was calculated as the ratio of the lowest, highest or mean ankle pressure to the highest arm pressure. RESULTS: Proportion of ABI(min)<0.90 was 10.3% in SED(HR) subjects versus 0.5% and 1.2%, respectively, in ACT(HR) and ACT(LR) groups. The averaged ABI value of each group was in the normal range in all groups (ABI>0.90) but was significantly lower in SED(HR) compared with all active participants (p<0.001). Regression lines from ABI(mean) versus age could lead to approximately +0.05 every 15 years of age in apparently healthy active participants (ACT(LR)). CONCLUSION: ABI at rest increases with the increase in age in the groups of low-risk asymptomatic middle-aged trained adults. The previously reported decrease in ABI with age is found only in SED(HR) subjects, and is very likely to rely on the increased prevalence of asymptomatic arterial disease in this group. The increase of ABI with age is consistent with the ‘physiological’ stiffness observed in ageing arteries even in the absence of ‘pathological’ atherosclerotic lesions. TRIAL REGISTRATION NUMBER: NIH clinicaltrial.gov: NCT01812343.
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spelling pubmed-51170222016-11-29 Ankle to brachial systolic pressure index at rest increases with age in asymptomatic physically active participants Congnard, Florian Abraham, Pierre Vincent, François Le tourneau, Thierry Carre, François Hupin, David Hamel, Jean François Vielle, Bruno Bruneau, Antoine BMJ Open Sport Exerc Med Research BACKGROUND: It is commonly acknowledged that the ability to use the ankle–brachial index (ABI), a reliable way to diagnose atherosclerosis, decreases with age in the general population. The aim of this study was to determine the relationship between resting ABI and age in different populations. METHODS: 674 physically active participants with (active high risk, ACT(HR)) or without (active low risk, ACT(LR)) cardiovascular risk factors or/and sedentary (SED) subjects, aged 20–70 years. Systolic arterial pressure was recorded at rest and simultaneously with automatic sphygmomanometers at the arms and ankles. ABI was calculated as the ratio of the lowest, highest or mean ankle pressure to the highest arm pressure. RESULTS: Proportion of ABI(min)<0.90 was 10.3% in SED(HR) subjects versus 0.5% and 1.2%, respectively, in ACT(HR) and ACT(LR) groups. The averaged ABI value of each group was in the normal range in all groups (ABI>0.90) but was significantly lower in SED(HR) compared with all active participants (p<0.001). Regression lines from ABI(mean) versus age could lead to approximately +0.05 every 15 years of age in apparently healthy active participants (ACT(LR)). CONCLUSION: ABI at rest increases with the increase in age in the groups of low-risk asymptomatic middle-aged trained adults. The previously reported decrease in ABI with age is found only in SED(HR) subjects, and is very likely to rely on the increased prevalence of asymptomatic arterial disease in this group. The increase of ABI with age is consistent with the ‘physiological’ stiffness observed in ageing arteries even in the absence of ‘pathological’ atherosclerotic lesions. TRIAL REGISTRATION NUMBER: NIH clinicaltrial.gov: NCT01812343. BMJ Publishing Group 2015-11-25 /pmc/articles/PMC5117022/ /pubmed/27900144 http://dx.doi.org/10.1136/bmjsem-2015-000081 Text en Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/ This is an Open Access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
spellingShingle Research
Congnard, Florian
Abraham, Pierre
Vincent, François
Le tourneau, Thierry
Carre, François
Hupin, David
Hamel, Jean François
Vielle, Bruno
Bruneau, Antoine
Ankle to brachial systolic pressure index at rest increases with age in asymptomatic physically active participants
title Ankle to brachial systolic pressure index at rest increases with age in asymptomatic physically active participants
title_full Ankle to brachial systolic pressure index at rest increases with age in asymptomatic physically active participants
title_fullStr Ankle to brachial systolic pressure index at rest increases with age in asymptomatic physically active participants
title_full_unstemmed Ankle to brachial systolic pressure index at rest increases with age in asymptomatic physically active participants
title_short Ankle to brachial systolic pressure index at rest increases with age in asymptomatic physically active participants
title_sort ankle to brachial systolic pressure index at rest increases with age in asymptomatic physically active participants
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5117022/
https://www.ncbi.nlm.nih.gov/pubmed/27900144
http://dx.doi.org/10.1136/bmjsem-2015-000081
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