Cargando…

Assessment of Mean Glandular Dose in Mammography System with Different Anode-Filter Combinations Using MCNP Code

BACKGROUND: X-ray mammography is one of the general methods for early detection of breast cancer. Since glandular tissue in the breast is sensitive to radiation and it increases the risk of cancer, the given dose to the patient is very important in mammography. OBJECTIVES: The aim of this study was...

Descripción completa

Detalles Bibliográficos
Autores principales: Gholamkar, Lida, Mowlavi, Ali Asghar, Sadeghi, Mahdi, Athari, Mitra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Kowsar 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5117115/
https://www.ncbi.nlm.nih.gov/pubmed/27895876
http://dx.doi.org/10.5812/iranjradiol.36484
_version_ 1782468765205659648
author Gholamkar, Lida
Mowlavi, Ali Asghar
Sadeghi, Mahdi
Athari, Mitra
author_facet Gholamkar, Lida
Mowlavi, Ali Asghar
Sadeghi, Mahdi
Athari, Mitra
author_sort Gholamkar, Lida
collection PubMed
description BACKGROUND: X-ray mammography is one of the general methods for early detection of breast cancer. Since glandular tissue in the breast is sensitive to radiation and it increases the risk of cancer, the given dose to the patient is very important in mammography. OBJECTIVES: The aim of this study was to determine the average absorbed dose of X-ray radiation in the glandular tissue of the breast during mammography examinations as well as investigating factors that influence the mean glandular dose (MGD). One of the precise methods for determination of MGD absorbed by the breast is Monte Carlo simulation method which is widely used to assess the dose. MATERIALS AND METHODS: We studied some different X-ray sources and exposure factors that affect the MGD. “Midi-future” digital mammography system with amorphous-selenium detector was simulated using the Monte Carlo N-particle extended (MCNPX) code. Different anode/filter combinations such as tungsten/silver (W/Ag), tungsten/rhodium (W/Rh), and rhodium/aluminium (Rh/Al) were simulated in this study. The voltage of X-ray tube ranged from 24 kV to 32 kV with 2 kV intervals and the breast phantom thickness ranged from 3 to 8 cm, and glandular fraction g varied from 10% to 100%. RESULTS: MGD was measured for different anode/filter combinations and the effects of changing tube voltage, phantom thickness, combination and glandular breast tissue on MGD were studied. As glandular g and X-ray tube voltage increased, the breast dose increased too, and the increase of breast phantom thickness led to the decrease of MGD. The obtained results for MGD were consistent with the result of Boone et al. that was previously reported. CONCLUSION: By comparing the results, we saw that W/Rh anode/filter combination is the best choice in breast mammography imaging because of the lowest delivered dose in comparison with W/Ag and Rh/Al. Moreover, breast thickness and g value have significant effects on MGD.
format Online
Article
Text
id pubmed-5117115
institution National Center for Biotechnology Information
language English
publishDate 2016
publisher Kowsar
record_format MEDLINE/PubMed
spelling pubmed-51171152016-11-28 Assessment of Mean Glandular Dose in Mammography System with Different Anode-Filter Combinations Using MCNP Code Gholamkar, Lida Mowlavi, Ali Asghar Sadeghi, Mahdi Athari, Mitra Iran J Radiol Physics BACKGROUND: X-ray mammography is one of the general methods for early detection of breast cancer. Since glandular tissue in the breast is sensitive to radiation and it increases the risk of cancer, the given dose to the patient is very important in mammography. OBJECTIVES: The aim of this study was to determine the average absorbed dose of X-ray radiation in the glandular tissue of the breast during mammography examinations as well as investigating factors that influence the mean glandular dose (MGD). One of the precise methods for determination of MGD absorbed by the breast is Monte Carlo simulation method which is widely used to assess the dose. MATERIALS AND METHODS: We studied some different X-ray sources and exposure factors that affect the MGD. “Midi-future” digital mammography system with amorphous-selenium detector was simulated using the Monte Carlo N-particle extended (MCNPX) code. Different anode/filter combinations such as tungsten/silver (W/Ag), tungsten/rhodium (W/Rh), and rhodium/aluminium (Rh/Al) were simulated in this study. The voltage of X-ray tube ranged from 24 kV to 32 kV with 2 kV intervals and the breast phantom thickness ranged from 3 to 8 cm, and glandular fraction g varied from 10% to 100%. RESULTS: MGD was measured for different anode/filter combinations and the effects of changing tube voltage, phantom thickness, combination and glandular breast tissue on MGD were studied. As glandular g and X-ray tube voltage increased, the breast dose increased too, and the increase of breast phantom thickness led to the decrease of MGD. The obtained results for MGD were consistent with the result of Boone et al. that was previously reported. CONCLUSION: By comparing the results, we saw that W/Rh anode/filter combination is the best choice in breast mammography imaging because of the lowest delivered dose in comparison with W/Ag and Rh/Al. Moreover, breast thickness and g value have significant effects on MGD. Kowsar 2016-08-01 /pmc/articles/PMC5117115/ /pubmed/27895876 http://dx.doi.org/10.5812/iranjradiol.36484 Text en Copyright © 2016, Tehran University of Medical Sciences and Iranian Society of Radiology http://creativecommons.org/licenses/by-nc/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/) which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited.
spellingShingle Physics
Gholamkar, Lida
Mowlavi, Ali Asghar
Sadeghi, Mahdi
Athari, Mitra
Assessment of Mean Glandular Dose in Mammography System with Different Anode-Filter Combinations Using MCNP Code
title Assessment of Mean Glandular Dose in Mammography System with Different Anode-Filter Combinations Using MCNP Code
title_full Assessment of Mean Glandular Dose in Mammography System with Different Anode-Filter Combinations Using MCNP Code
title_fullStr Assessment of Mean Glandular Dose in Mammography System with Different Anode-Filter Combinations Using MCNP Code
title_full_unstemmed Assessment of Mean Glandular Dose in Mammography System with Different Anode-Filter Combinations Using MCNP Code
title_short Assessment of Mean Glandular Dose in Mammography System with Different Anode-Filter Combinations Using MCNP Code
title_sort assessment of mean glandular dose in mammography system with different anode-filter combinations using mcnp code
topic Physics
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5117115/
https://www.ncbi.nlm.nih.gov/pubmed/27895876
http://dx.doi.org/10.5812/iranjradiol.36484
work_keys_str_mv AT gholamkarlida assessmentofmeanglandulardoseinmammographysystemwithdifferentanodefiltercombinationsusingmcnpcode
AT mowlavialiasghar assessmentofmeanglandulardoseinmammographysystemwithdifferentanodefiltercombinationsusingmcnpcode
AT sadeghimahdi assessmentofmeanglandulardoseinmammographysystemwithdifferentanodefiltercombinationsusingmcnpcode
AT atharimitra assessmentofmeanglandulardoseinmammographysystemwithdifferentanodefiltercombinationsusingmcnpcode