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Assessing the Potential Effects of Active Site Mg(2+) Ions in the glmS Ribozyme–Cofactor Complex

[Image: see text] Ribozymes employ diverse catalytic strategies in their self-cleavage mechanisms, including the use of divalent metal ions. This work explores the effects of Mg(2+) ions in the active site of the glmS ribozyme–GlcN6P cofactor complex using computational methods. Deleterious and pote...

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Detalles Bibliográficos
Autores principales:	Zhang, Sixue, Stevens, David R., Goyal, Puja, Bingaman, Jamie L., Bevilacqua, Philip C., Hammes-Schiffer, Sharon
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2016
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5117136/ https://www.ncbi.nlm.nih.gov/pubmed/27677922 http://dx.doi.org/10.1021/acs.jpclett.6b01854

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