New links between SOD1 and metabolic dysfunction from a yeast model of amyotrophic lateral sclerosis

A number of genes have been linked to familial forms of the fatal motor neuron disease amyotrophic lateral sclerosis (ALS). Over 150 mutations within the gene encoding superoxide dismutase 1 (SOD1) have been implicated in ALS, but why such mutations lead to ALS-associated cellular dysfunction is unc...

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Detalles Bibliográficos
Autores principales: Bastow, Emma L., Peswani, Amber R., Tarrant, Daniel S. J., Pentland, Daniel R., Chen, Xi, Morgan, Alan, Staniforth, Gemma L., Tullet, Jennifer M., Rowe, Michelle L., Howard, Mark J., Tuite, Mick F., Gourlay, Campbell W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5117206/
https://www.ncbi.nlm.nih.gov/pubmed/27656112
http://dx.doi.org/10.1242/jcs.190298

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5117206/
https://www.ncbi.nlm.nih.gov/pubmed/27656112
http://dx.doi.org/10.1242/jcs.190298

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