iDamIDseq and iDEAR: an improved method and computational pipeline to profile chromatin-binding proteins

DNA adenine methyltransferase identification (DamID) has emerged as an alternative method to profile protein-DNA interactions; however, critical issues limit its widespread applicability. Here, we present iDamIDseq, a protocol that improves specificity and sensitivity by inverting the steps DpnI-Dpn...

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Detalles Bibliográficos
Autores principales: Gutierrez-Triana, Jose Arturo, Mateo, Juan L., Ibberson, David, Ryu, Soojin, Wittbrodt, Joachim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2016
Materias:
Techniques and Resources
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5117216/
https://www.ncbi.nlm.nih.gov/pubmed/27707796
http://dx.doi.org/10.1242/dev.139261

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5117216/
https://www.ncbi.nlm.nih.gov/pubmed/27707796
http://dx.doi.org/10.1242/dev.139261

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