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iDamIDseq and iDEAR: an improved method and computational pipeline to profile chromatin-binding proteins
DNA adenine methyltransferase identification (DamID) has emerged as an alternative method to profile protein-DNA interactions; however, critical issues limit its widespread applicability. Here, we present iDamIDseq, a protocol that improves specificity and sensitivity by inverting the steps DpnI-Dpn...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Company of Biologists Ltd
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5117216/ https://www.ncbi.nlm.nih.gov/pubmed/27707796 http://dx.doi.org/10.1242/dev.139261 |