Cargando…

Hippocampal activation of microglia may underlie the shared neurobiology of comorbid posttraumatic stress disorder and chronic pain

The high comorbidity rates of posttraumatic stress disorder and chronic pain have been widely reported, but the underlying mechanisms remain unclear. Emerging evidence suggested that an excess of inflammatory immune activities in the hippocampus involved in the progression of both posttraumatic stre...

Descripción completa

Detalles Bibliográficos
Autores principales:	Sun, Rao, Zhang, Zuoxia, Lei, Yishan, Liu, Yue, Lu, Cui’e, Rong, Hui, Sun, Yu’e, Zhang, Wei, Ma, Zhengliang, Gu, Xiaoping
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	SAGE Publications 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5117253/ https://www.ncbi.nlm.nih.gov/pubmed/27852966 http://dx.doi.org/10.1177/1744806916679166

Ejemplares similares

Mas-Related Gene (Mrg) C Activation Attenuates Bone Cancer Pain via Modulating Gi and NR2B
por: Sun, Yu’e, et al.
Publicado: (2016)

Intraoperative electroacupuncture relieves remifentanil-induced postoperative hyperalgesia via inhibiting spinal glial activation in rats
por: Shi, Changxi, et al.
Publicado: (2017)

Shared Molecular Genetic Mechanisms Underlie Endometriosis and Migraine Comorbidity
por: Adewuyi, Emmanuel O., et al.
Publicado: (2020)

Hippocampal Activated Microglia May Contribute to Blood–Brain Barrier Impairment and Cognitive Dysfunction in Post-Traumatic Stress Disorder-Like Rats
por: Ni, Kun, et al.
Publicado: (2022)

Anxiety-induced hyperalgesia in female rats is mediated by cholecystokinin 2 receptor in rostral ventromedial medulla and spinal 5-hydroxytryptamine 2B receptor
por: Jiang, Ming, et al.
Publicado: (2019)

Microglia and astrocytes underlie neuroinflammation and synaptic susceptibility in autism spectrum disorder
por: Xiong, Yue, et al.
Publicado: (2023)

Neurobiological findings in posttraumatic stress disorder: a review
por: Vedantham, Kumar, et al.
Publicado: (2000)

Pretreatment of the ROS Inhibitor Phenyl-N-tert-butylnitrone Alleviates Sleep Deprivation-Induced Hyperalgesia by Suppressing Microglia Activation and NLRP3 Inflammasome Activity in the Spinal Dorsal Cord
por: Huang, Yulin, et al.
Publicado: (2022)

GPR30 receptor promotes preoperative anxiety-induced postoperative hyperalgesia by up-regulating GABA(A)-α4β1δ subunits in periaqueductal gray in female rats
por: Jiang, Ming, et al.
Publicado: (2020)

Stress-induced precocious aging in PD-patient iPSC-derived NSCs may underlie the pathophysiology of Parkinson’s disease
por: Zhu, Liang, et al.
Publicado: (2019)

Preoperative anxiety-induced glucocorticoid signaling reduces GABAergic markers in spinal cord and promotes postoperative hyperalgesia by affecting neuronal PAS domain protein 4
por: Wu, Hao, et al.
Publicado: (2019)

Traumatic stress and the circadian system: neurobiology, timing and treatment of posttraumatic chronodisruption
por: Agorastos, Agorastos, et al.
Publicado: (2020)

Neurobiological mechanisms underlying delayed expression of posttraumatic stress disorder: A scoping review
por: Smid, Geert E, et al.
Publicado: (2022)

Aberrant imprinting may underlie evolution of parthenogenesis
por: Kirioukhova, Olga, et al.
Publicado: (2018)

Shared behavioral mechanisms underlie C. elegans aggregation and swarming
por: Ding, Siyu Serena, et al.
Publicado: (2019)

Medication-Enhanced Psychotherapy for Posttraumatic Stress Disorder: Recent Findings on Oxytocin’s Involvement in the Neurobiology and Treatment of Posttraumatic Stress Disorder
por: Preckel, Katrin, et al.
Publicado: (2021)

How resource sharing resists scarcity: the role of cognitive empathy and its neurobiological mechanisms
por: Cui, Fang, et al.
Publicado: (2022)

Shared Genomic Regions Underlie Natural Variation in Diverse Toxin Responses
por: Evans, Kathryn S., et al.
Publicado: (2018)

Shared mechanisms underlie mental imagery and motor planning
por: Bennet, Rotem, et al.
Publicado: (2022)

Shared mental representations underlie metaphorical sound concepts
por: Rosi, Victor, et al.
Publicado: (2023)

Reaction of the Hippocampal Microglia to Hyperbaric Oxygen
por: Kirik, O. V., et al.
Publicado: (2022)

Up-Regulation of Th17 Cells May Underlie Inhibition of Treg Development Caused by Immunization with Activated Syngeneic T Cells
por: Wang, Li, et al.
Publicado: (2011)

Alterations in hippocampal subfield and amygdala subregion volumes in posttraumatic subjects with and without posttraumatic stress disorder
por: Zhang, Lianqing, et al.
Publicado: (2021)

Posttraumatic stress disorder under ongoing threat: a review of neurobiological and neuroendocrine findings
por: Fragkaki, Iro, et al.
Publicado: (2016)

Unveiling the Secrets of the Stressed Hippocampus: Exploring Proteomic Changes and Neurobiology of Posttraumatic Stress Disorder
por: Nieto-Quero, Andrea, et al.
Publicado: (2023)

Dehydrocorydaline attenuates bone cancer pain by shifting microglial M1/M2 polarization toward the M2 phenotype
por: Huo, Wenwen, et al.
Publicado: (2018)

OBESITY MAY UNDERLIE SKELETAL MUSCLE AUTOIMMUNITY IN OLDER ADULTS
por: Zhang, Tan, et al.
Publicado: (2022)

Gender Differences in the Neurobiology of Anxiety: Focus on Adult Hippocampal Neurogenesis
por: Marques, Alessandra Aparecida, et al.
Publicado: (2016)

Intrathecal Injection of Spironolactone Attenuates Radicular Pain by Inhibition of Spinal Microglia Activation in a Rat Model
por: Sun, Yu-e, et al.
Publicado: (2012)

A tale of two comorbidities: Understanding the neurobiology of depression and pain
por: Narasimhan, Meera, et al.
Publicado: (2010)

Elucidating the Neurobiologic Etiology of Comorbid PTSD and Substance Use Disorders
por: Hinckley, Jesse D., et al.
Publicado: (2022)

Noncanonical functions of Ku may underlie essentiality in human cells
por: Kelly, Rachel D., et al.
Publicado: (2023)

Hippocampal sharp wave ripples underlie stress susceptibility in male mice
por: Kuga, Nahoko, et al.
Publicado: (2023)

Differences in Prediction May Underlie Language Disorder in Autism
por: Ellis Weismer, Susan, et al.
Publicado: (2022)

Hippocampal transcriptome-wide association study and neurobiological pathway analysis for Alzheimer’s disease
por: Liu, Nana, et al.
Publicado: (2021)

Comorbidity of asthma and hypertension may be mediated by shared genetic dysregulation and drug side effects
por: Zolotareva, Olga, et al.
Publicado: (2019)

Neurobiological Features of Posttraumatic Stress Disorder (PTSD) and Their Role in Understanding Adaptive Behavior and Stress Resilience
por: Toledo, Felippe, et al.
Publicado: (2022)

Is there a shared neurobiology between aggression and Internet addiction disorder?
por: Hahn, Changtae, et al.
Publicado: (2014)

N-acetyl-cysteine attenuates remifentanil-induced postoperative hyperalgesia via inhibiting matrix metalloproteinase-9 in dorsal root ganglia
por: Liu, Yue, et al.
Publicado: (2017)

Antinociceptive effects of caloric restriction on post-incisional pain in nonobese rats
por: Liu, Yue, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_p71d1m7m4f8lrfr36iub9g817o