Analysis of allelic expression patterns in clonal somatic cells by single-cell RNA-seq

Cellular heterogeneity can emerge from the expression of only one parental allele. However, it has remained controversial whether, or to what degree, random monoallelic expression of autosomal genes (aRME) is mitotically inherited (clonal) or stochastic (dynamic) in somatic cells, particularly in vi...

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Detalles Bibliográficos
Autores principales: Reinius, Björn, Mold, Jeff E., Ramsköld, Daniel, Deng, Qiaolin, Johnsson, Per, Michaëlsson, Jakob, Frisén, Jonas, Sandberg, Rickard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5117254/
https://www.ncbi.nlm.nih.gov/pubmed/27668657
http://dx.doi.org/10.1038/ng.3678

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5117254/
https://www.ncbi.nlm.nih.gov/pubmed/27668657
http://dx.doi.org/10.1038/ng.3678

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