Pulmonary endothelial activation caused by extracellular histones contributes to neutrophil activation in acute respiratory distress syndrome

BACKGROUND: During the acute respiratory distress syndrome (ARDS), neutrophils play a central role in the pathogenesis, and their activation requires interaction with the endothelium. Extracellular histones have been recognized as pivotal inflammatory mediators. This study was to investigate the rol...

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Detalles Bibliográficos
Autores principales: Zhang, Yanlin, Guan, Li, Yu, Jie, Zhao, Zanmei, Mao, Lijun, Li, Shuqiang, Zhao, Jinyuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5117496/
https://www.ncbi.nlm.nih.gov/pubmed/27871277
http://dx.doi.org/10.1186/s12931-016-0472-y

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