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Coexistence of iAMP21 and ETV6-RUNX1 fusion in an adolescent with B cell acute lymphoblastic leukemia: literature review of six additional cases
BACKGROUND: Intrachromosomal amplification of chromosome 21 (iAMP21) results from breakage-fusion-bridge cycles and chromothripsis is a distinct marker of a subgroup of B cell acute lymphoblastic leukemia (B-ALL) cases associated with a poor prognosis. iAMP21 accounts for 2% of pediatric B-ALL and o...
Autores principales: | Gu, Jun, Reynolds, Alexandra, Fang, Lianghua, DeGraffenreid, Corrie, Sterns, Kenneth, Patel, Keyur P., Medeiros, L. Jeffrey, Lin, Pei, Lu, Xinyan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5117506/ https://www.ncbi.nlm.nih.gov/pubmed/27895713 http://dx.doi.org/10.1186/s13039-016-0294-0 |
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