Transcriptome analysis reveals manifold mechanisms of cyst development in ADPKD

BACKGROUND: Autosomal dominant polycystic kidney disease (ADPKD) causes progressive loss of renal function in adults as a consequence of the accumulation of cysts. ADPKD is the most common genetic cause of end-stage renal disease. Mutations in polycystin-1 occur in 87% of cases of ADPKD and mutation...

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Detalles Bibliográficos
Autores principales: de Almeida, Rita M. C., Clendenon, Sherry G., Richards, William G., Boedigheimer, Michael, Damore, Michael, Rossetti, Sandro, Harris, Peter C., Herbert, Britney-Shea, Xu, Wei Min, Wandinger-Ness, Angela, Ward, Heather H., Glazier, James A., Bacallao, Robert L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Primary Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5117508/
https://www.ncbi.nlm.nih.gov/pubmed/27871310
http://dx.doi.org/10.1186/s40246-016-0095-x

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