Inhibition of STAT3- and MAPK-dependent PGE(2) synthesis ameliorates phagocytosis of fibrillar β-amyloid peptide (1-42) via EP2 receptor in EMF-stimulated N9 microglial cells

BACKGROUND: Prostaglandin E(2) (PGE(2))-involved neuroinflammatory processes are prevalent in several neurological conditions and diseases. Amyloid burden is correlated with the activation of E-prostanoid (EP) 2 receptors by PGE(2) in Alzheimer’s disease. We previously demonstrated that electromagne...

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Detalles Bibliográficos
Autores principales: He, Gen-Lin, Luo, Zhen, Shen, Ting-Ting, Li, Ping, Yang, Ju, Luo, Xue, Chen, Chun-Hai, Gao, Peng, Yang, Xue-Sen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5117690/
https://www.ncbi.nlm.nih.gov/pubmed/27871289
http://dx.doi.org/10.1186/s12974-016-0762-9

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