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ATP Hydrolysis Induced Conformational Changes in the Vitamin B(12) Transporter BtuCD Revealed by MD Simulations

ATP binding cassette (ABC) transporters utilize the energy of ATP hydrolysis to uni-directionally transport substrates across cell membrane. ATP hydrolysis occurs at the nucleotide-binding domain (NBD) dimer interface of ABC transporters, whereas substrate translocation takes place at the translocat...

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Detalles Bibliográficos
Autores principales:	Pan, Chao, Weng, Jingwei, Wang, Wenning
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5117765/ https://www.ncbi.nlm.nih.gov/pubmed/27870912 http://dx.doi.org/10.1371/journal.pone.0166980

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