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Tumor suppressor ING4 inhibits estrogen receptor activity in breast cancer cells

Resistance to antiestrogen therapy remains a significant problem in breast cancer. Low expression of inhibitor of growth 4 (ING4) in primary tumors has been correlated with increased rates of recurrence in estrogen receptor-positive (ER+) breast cancer patients, suggesting a role for ING4 in ER sign...

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Detalles Bibliográficos
Autores principales: Keenen, Madeline M, Kim, Suwon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5117803/
https://www.ncbi.nlm.nih.gov/pubmed/27895513
http://dx.doi.org/10.2147/BCTT.S119691