DUOX1 silencing in lung cancer promotes EMT, cancer stem cell characteristics and invasive properties

Dual oxidase 1 (DUOX1) is an oxidant-generating enzyme within the airway epithelium that participates in innate airway host defense and epithelial homeostasis. Recent studies indicate that DUOX1 is suppressed in lung cancers by epigenetic silencing, although the importance of DUOX1 silencing in lung...

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Detalles Bibliográficos
Autores principales: Little, A C, Sham, D, Hristova, M, Danyal, K, Heppner, D E, Bauer, R A, Sipsey, L M, Habibovic, A, van der Vliet, A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5117847/
https://www.ncbi.nlm.nih.gov/pubmed/27694834
http://dx.doi.org/10.1038/oncsis.2016.61

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