GPR133 (ADGRD1), an adhesion G-protein-coupled receptor, is necessary for glioblastoma growth

Glioblastoma (GBM) is a deadly primary brain malignancy with extensive intratumoral hypoxia. Hypoxic regions of GBM contain stem-like cells and are associated with tumor growth and angiogenesis. The molecular mechanisms that regulate tumor growth in hypoxic conditions are incompletely understood. He...

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Detalles Bibliográficos
Autores principales: Bayin, N S, Frenster, J D, Kane, J R, Rubenstein, J, Modrek, A S, Baitalmal, R, Dolgalev, I, Rudzenski, K, Scarabottolo, L, Crespi, D, Redaelli, L, Snuderl, M, Golfinos, J G, Doyle, W, Pacione, D, Parker, E C, Chi, A S, Heguy, A, MacNeil, D J, Shohdy, N, Zagzag, D, Placantonakis, D G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5117849/
https://www.ncbi.nlm.nih.gov/pubmed/27775701
http://dx.doi.org/10.1038/oncsis.2016.63

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