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A FISH-based method for assessment of HER-2 amplification status in breast cancer circulating tumor cells following CellSearch isolation

INTRODUCTION: Amplification of the HER-2/neu (HER-2) proto-oncogene occurs in 10%–15% of primary breast cancer, leading to an activated HER-2 receptor, augmenting growth of cancer cells. Tumor classification is determined in primary tumor tissue and metastatic biopsies. However, malignant cells tend...

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Detalles Bibliográficos
Autores principales:	Frithiof, Henrik, Aaltonen, Kristina, Rydén, Lisa
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2016
Materias:	Methodology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5117892/ https://www.ncbi.nlm.nih.gov/pubmed/27895501 http://dx.doi.org/10.2147/OTT.S118502

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