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Somatically Hypermutated Plasmodium-Specific IgM(+) Memory B Cells Are Rapid, Plastic, Early Responders upon Malaria Rechallenge

Humoral immunity consists of pre-existing antibodies expressed by long-lived plasma cells and rapidly reactive memory B cells (MBC). Recent studies of MBC development and function after protein immunization have uncovered significant MBC heterogeneity. To clarify functional roles for distinct MBC su...

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Detalles Bibliográficos
Autores principales:	Krishnamurty, Akshay T., Thouvenel, Christopher D., Portugal, Silvia, Keitany, Gladys J., Kim, Karen S., Holder, Anthony, Crompton, Peter D., Rawlings, David J., Pepper, Marion
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cell Press 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5118370/ https://www.ncbi.nlm.nih.gov/pubmed/27473412 http://dx.doi.org/10.1016/j.immuni.2016.06.014

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