Insulin Induces Relaxation and Decreases Hydrogen Peroxide-Induced Vasoconstriction in Human Placental Vascular Bed in a Mechanism Mediated by Calcium-Activated Potassium Channels and L-Arginine/Nitric Oxide Pathways

HIGHLIGHTS: Short-term incubation with insulin increases the L-arginine transport in HUVECs. Short-term incubation with insulin increases the NO synthesis in HUVECs. Insulin induces relaxation in human placental vascular bed. Insulin attenuates the constriction induced by hydrogen peroxide in human...

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Detalles Bibliográficos
Autores principales: Cabrera, Lissette, Saavedra, Andrea, Rojas, Susana, Cid, Marcela, Valenzuela, Cristina, Gallegos, David, Careaga, Pamela, Basualto, Emerita, Haensgen, Astrid, Peña, Eduardo, Rivas, Coralia, Vera, Juan Carlos, Gallardo, Victoria, Zúñiga, Leandro, Escudero, Carlos, Sobrevia, Luis, Wareing, Mark, González, Marcelo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Physiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5118463/
https://www.ncbi.nlm.nih.gov/pubmed/27920724
http://dx.doi.org/10.3389/fphys.2016.00529

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