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Nanoscale Structure and Spectroscopic Probing of Aβ1-40 Fibril Bundle Formation

Amyloid plaques composed of fibrillar Amyloid-β (Aβ) are hallmarks of Alzheimer's disease. However, Aβ fibrils are morphologically heterogeneous. Conformation sensitive luminescent conjugated oligothiophenes (LCOs) are versatile tools for monitoring such fibril polymorphism in vivo and in vitro...

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Detalles Bibliográficos
Autores principales:	Psonka-Antonczyk, Katarzyna M., Hammarström, Per, Johansson, Leif B. G., Lindgren, Mikael, Stokke, Bjørn T., Nilsson, K. Peter R., Nyström, Sofie
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2016
Materias:	Chemistry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5118468/ https://www.ncbi.nlm.nih.gov/pubmed/27921029 http://dx.doi.org/10.3389/fchem.2016.00044

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