ROS-Responsive Mitochondria-Targeting Blended Nanoparticles: Chemo- and Photodynamic Synergistic Therapy for Lung Cancer with On-Demand Drug Release upon Irradiation with a Single Light Source

Mitochondria in cancer cells maintain a more negative membrane potential than normal cells. Mitochondria are the primary source of cellular reactive oxygen species (ROS), which are necessary for photodynamic therapy. Thus, the strategy of targeting mitochondria can maximize the photodynamic therapeu...

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Detalles Bibliográficos
Autores principales: Yue, Caixia, Yang, Yuming, Zhang, Chunlei, Alfranca, Gabriel, Cheng, Shangli, Ma, Lijun, Liu, Yanlei, Zhi, Xiao, Ni, Jian, Jiang, Weihua, Song, Jie, de la Fuente, Jesús M., Cui, Daxiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5118600/
https://www.ncbi.nlm.nih.gov/pubmed/27877240
http://dx.doi.org/10.7150/thno.15433

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