Identification of inhibitors that dually target the new permeability pathway and dihydroorotate dehydrogenase in the blood stage of Plasmodium falciparum

Plasmodium parasites are responsible for the devastating disease malaria that affects hundreds of millions of people each year. Blood stage parasites establish new permeability pathways (NPPs) in infected red blood cell membranes to facilitate the uptake of nutrients and removal of parasite waste pr...

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Detalles Bibliográficos
Autores principales: Dickerman, Benjamin K., Elsworth, Brendan, Cobbold, Simon A., Nie, Catherine Q., McConville, Malcolm J., Crabb, Brendan S., Gilson, Paul R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5118696/
https://www.ncbi.nlm.nih.gov/pubmed/27874068
http://dx.doi.org/10.1038/srep37502

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5118696/
https://www.ncbi.nlm.nih.gov/pubmed/27874068
http://dx.doi.org/10.1038/srep37502

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