Combinational Immunotherapy with Allo-DRibble Vaccines and Anti-OX40 Co-Stimulation Leads to Generation of Cross-Reactive Effector T Cells and Tumor Regression

It is well-known that vaccines comprising of irradiated whole tumor cells or tumor-derived heat shock proteins can generate tumor-specific immune responses. In contrast, we showed recently that vaccines composed of autophagosomes (DRibbles) derived from syngeneic sarcomas could induce cross-reactive...

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Detalles Bibliográficos
Autores principales: Yu, Guangjie, Li, Yuhuan, Cui, Zhihua, Morris, Nicholas P., Weinberg, Andrew D., Fox, Bernard A., Urba, Walter J., Wang, Lixin, Hu, Hong-Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5118714/
https://www.ncbi.nlm.nih.gov/pubmed/27874054
http://dx.doi.org/10.1038/srep37558

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5118714/
https://www.ncbi.nlm.nih.gov/pubmed/27874054
http://dx.doi.org/10.1038/srep37558

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