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Electrical Stimulus Controlled Binding/Unbinding of Human Thrombin-Aptamer Complex

The binding/unbinding of the human thrombin and its 15-mer single stranded DNA aptamer, under the application of external stimulus in the form of electrostatic potential/electric field, is investigated by a combination of continuum analysis and atomistic molecular dynamics simulation. In agreement w...

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Detalles Bibliográficos
Autores principales:	Gosai, Agnivo, Ma, Xiao, Balasubramanian, Ganesh, Shrotriya, Pranav
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5118750/ https://www.ncbi.nlm.nih.gov/pubmed/27874042 http://dx.doi.org/10.1038/srep37449

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