Histone Deacetylase Inhibitor Trichostatin a Promotes the Apoptosis of Osteosarcoma Cells through p53 Signaling Pathway Activation

Purpose: The purpose of this study was to investigate the profile of histone deacetylase (HDAC) activity and expression in osteosarcoma cells and tissues from osteosarcoma patients and to examine the mechanism by which a histone deacetylase (HDAC) inhibitor, Trichostatin A (TSA), promotes the apopto...

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Detalles Bibliográficos
Autores principales: Deng, Zhantao, Liu, Xiaozhou, Jin, Jiewen, Xu, Haidong, Gao, Qian, Wang, Yong, Zhao, Jianning
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5118776/
https://www.ncbi.nlm.nih.gov/pubmed/27877082
http://dx.doi.org/10.7150/ijbs.16569

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5118776/
https://www.ncbi.nlm.nih.gov/pubmed/27877082
http://dx.doi.org/10.7150/ijbs.16569

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