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Histone Deacetylase Inhibitor Trichostatin a Promotes the Apoptosis of Osteosarcoma Cells through p53 Signaling Pathway Activation
Purpose: The purpose of this study was to investigate the profile of histone deacetylase (HDAC) activity and expression in osteosarcoma cells and tissues from osteosarcoma patients and to examine the mechanism by which a histone deacetylase (HDAC) inhibitor, Trichostatin A (TSA), promotes the apopto...
Autores principales: | Deng, Zhantao, Liu, Xiaozhou, Jin, Jiewen, Xu, Haidong, Gao, Qian, Wang, Yong, Zhao, Jianning |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Ivyspring International Publisher
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5118776/ https://www.ncbi.nlm.nih.gov/pubmed/27877082 http://dx.doi.org/10.7150/ijbs.16569 |
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