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A mouse model of hereditary hemorrhagic telangiectasia generated by transmammary-delivered immunoblocking of BMP9 and BMP10

Hereditary hemorrhagic telangiectasia (HHT) is a potentially life-threatening genetic vascular disorder caused by loss-of-function mutations in the genes encoding activin receptor-like kinase 1 (ALK1), endoglin, Smad4, and bone morphogenetic protein 9 (BMP9). Injections of mouse neonates with BMP9/1...

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Detalles Bibliográficos
Autores principales:	Ruiz, Santiago, Zhao, Haitian, Chandakkar, Pallavi, Chatterjee, Prodyot K., Papoin, Julien, Blanc, Lionel, Metz, Christine N., Campagne, Fabien, Marambaud, Philippe
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5118799/ https://www.ncbi.nlm.nih.gov/pubmed/27874028 http://dx.doi.org/10.1038/srep37366

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