Effects of Arsenic Trioxide on Minor Progressive High-Grade Osteosarcoma of the Extremities Metastatic to the Lung: Results of 39 Patients Treated in a Single Institution

Patients who mildly progressed after first-line chemotherapy were administered arsenic trioxide (ATO) 5–10 mg intravenously daily. Thirty-nine patients were finally enrolled in the study, of whom 19 patients received first-line chemotherapy with ATO infusion while 20 patients did not. Progression-fr...

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Autores principales: Xie, Lu, Guo, Wei, Tang, Xiaodong, Yang, Yi, Xu, Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: S. Karger AG 2016
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5118832/
https://www.ncbi.nlm.nih.gov/pubmed/27920692
http://dx.doi.org/10.1159/000448705
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author Xie, Lu
Guo, Wei
Tang, Xiaodong
Yang, Yi
Xu, Jie
author_facet Xie, Lu
Guo, Wei
Tang, Xiaodong
Yang, Yi
Xu, Jie
author_sort Xie, Lu
collection PubMed
description Patients who mildly progressed after first-line chemotherapy were administered arsenic trioxide (ATO) 5–10 mg intravenously daily. Thirty-nine patients were finally enrolled in the study, of whom 19 patients received first-line chemotherapy with ATO infusion while 20 patients did not. Progression-free survival at 4 months was 89.2 and 62.7% (p = 0.043) for the ATO group and the control group, respectively, while the 2-year overall survival was 61 and 16.4% (p = 0.032).
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spelling pubmed-51188322016-12-05 Effects of Arsenic Trioxide on Minor Progressive High-Grade Osteosarcoma of the Extremities Metastatic to the Lung: Results of 39 Patients Treated in a Single Institution Xie, Lu Guo, Wei Tang, Xiaodong Yang, Yi Xu, Jie Case Rep Oncol Case Report Patients who mildly progressed after first-line chemotherapy were administered arsenic trioxide (ATO) 5–10 mg intravenously daily. Thirty-nine patients were finally enrolled in the study, of whom 19 patients received first-line chemotherapy with ATO infusion while 20 patients did not. Progression-free survival at 4 months was 89.2 and 62.7% (p = 0.043) for the ATO group and the control group, respectively, while the 2-year overall survival was 61 and 16.4% (p = 0.032). S. Karger AG 2016-10-17 /pmc/articles/PMC5118832/ /pubmed/27920692 http://dx.doi.org/10.1159/000448705 Text en Copyright © 2016 by S. Karger AG, Basel http://creativecommons.org/licenses/by-nc/4.0/ This article is licensed under the Creative Commons Attribution-NonCommercial-4.0 International License (CC BY-NC) (http://www.karger.com/Services/OpenAccessLicense). Usage and distribution for commercial purposes requires written permission.
spellingShingle Case Report
Xie, Lu
Guo, Wei
Tang, Xiaodong
Yang, Yi
Xu, Jie
Effects of Arsenic Trioxide on Minor Progressive High-Grade Osteosarcoma of the Extremities Metastatic to the Lung: Results of 39 Patients Treated in a Single Institution
title Effects of Arsenic Trioxide on Minor Progressive High-Grade Osteosarcoma of the Extremities Metastatic to the Lung: Results of 39 Patients Treated in a Single Institution
title_full Effects of Arsenic Trioxide on Minor Progressive High-Grade Osteosarcoma of the Extremities Metastatic to the Lung: Results of 39 Patients Treated in a Single Institution
title_fullStr Effects of Arsenic Trioxide on Minor Progressive High-Grade Osteosarcoma of the Extremities Metastatic to the Lung: Results of 39 Patients Treated in a Single Institution
title_full_unstemmed Effects of Arsenic Trioxide on Minor Progressive High-Grade Osteosarcoma of the Extremities Metastatic to the Lung: Results of 39 Patients Treated in a Single Institution
title_short Effects of Arsenic Trioxide on Minor Progressive High-Grade Osteosarcoma of the Extremities Metastatic to the Lung: Results of 39 Patients Treated in a Single Institution
title_sort effects of arsenic trioxide on minor progressive high-grade osteosarcoma of the extremities metastatic to the lung: results of 39 patients treated in a single institution
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5118832/
https://www.ncbi.nlm.nih.gov/pubmed/27920692
http://dx.doi.org/10.1159/000448705
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