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A Case of “en bloc” Excision of a Chest Wall Leiomyosarcoma and Closure of the Defect with Non-Cross-Linked Collagen Matrix (Egis(®))

Sarcomas arising from the chest wall account for less than 20% of all soft tissue sarcomas, and at this site, primitive tumors are the most frequent to occur. Leiomyosarcoma is a malignant smooth muscle tumor and the best outcomes are achieved with wide surgical excision. Although advancements have...

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Autores principales: Rastrelli, Marco, Tropea, Saveria, Spina, Romina, Costa, Alessandra, Stramare, Roberto, Mocellin, Simone, Bonavina, Maria Giuseppina, Rossi, Carlo Riccardo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: S. Karger AG 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5118835/
https://www.ncbi.nlm.nih.gov/pubmed/27920698
http://dx.doi.org/10.1159/000452147
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author Rastrelli, Marco
Tropea, Saveria
Spina, Romina
Costa, Alessandra
Stramare, Roberto
Mocellin, Simone
Bonavina, Maria Giuseppina
Rossi, Carlo Riccardo
author_facet Rastrelli, Marco
Tropea, Saveria
Spina, Romina
Costa, Alessandra
Stramare, Roberto
Mocellin, Simone
Bonavina, Maria Giuseppina
Rossi, Carlo Riccardo
author_sort Rastrelli, Marco
collection PubMed
description Sarcomas arising from the chest wall account for less than 20% of all soft tissue sarcomas, and at this site, primitive tumors are the most frequent to occur. Leiomyosarcoma is a malignant smooth muscle tumor and the best outcomes are achieved with wide surgical excision. Although advancements have been made in treatment protocols, leiomyosarcoma remains one of the more difficult soft tissue sarcoma to treat. Currently, general local control is obtained with surgical treatment with wide negative margins. We describe the case of a 50-year-old man who underwent a chest wall resection involving a wide portion of the pectoralis major and minor muscle, the serratus and part of the second, third and fourth ribs of the left side. The full-thickness chest wall defect of 10 × 8 cm was closed using a non-cross-linked acellular dermal matrix (Egis(®)) placed in two layers, beneath the rib plane and over it. A successful repair was achieved with no incisional herniation and with complete tissue regeneration, allowing natural respiratory movements. No complications were observed in the postoperative course. Biological non-cross-linked matrix, derived from porcine dermis, behaves like a scaffold supporting tissue regeneration; it can be successfully used as an alternative to synthetic mesh for chest wall reconstruction.
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spelling pubmed-51188352016-12-05 A Case of “en bloc” Excision of a Chest Wall Leiomyosarcoma and Closure of the Defect with Non-Cross-Linked Collagen Matrix (Egis(®)) Rastrelli, Marco Tropea, Saveria Spina, Romina Costa, Alessandra Stramare, Roberto Mocellin, Simone Bonavina, Maria Giuseppina Rossi, Carlo Riccardo Case Rep Oncol Case Report Sarcomas arising from the chest wall account for less than 20% of all soft tissue sarcomas, and at this site, primitive tumors are the most frequent to occur. Leiomyosarcoma is a malignant smooth muscle tumor and the best outcomes are achieved with wide surgical excision. Although advancements have been made in treatment protocols, leiomyosarcoma remains one of the more difficult soft tissue sarcoma to treat. Currently, general local control is obtained with surgical treatment with wide negative margins. We describe the case of a 50-year-old man who underwent a chest wall resection involving a wide portion of the pectoralis major and minor muscle, the serratus and part of the second, third and fourth ribs of the left side. The full-thickness chest wall defect of 10 × 8 cm was closed using a non-cross-linked acellular dermal matrix (Egis(®)) placed in two layers, beneath the rib plane and over it. A successful repair was achieved with no incisional herniation and with complete tissue regeneration, allowing natural respiratory movements. No complications were observed in the postoperative course. Biological non-cross-linked matrix, derived from porcine dermis, behaves like a scaffold supporting tissue regeneration; it can be successfully used as an alternative to synthetic mesh for chest wall reconstruction. S. Karger AG 2016-10-20 /pmc/articles/PMC5118835/ /pubmed/27920698 http://dx.doi.org/10.1159/000452147 Text en Copyright © 2016 by S. Karger AG, Basel http://creativecommons.org/licenses/by-nc/4.0/ This article is licensed under the Creative Commons Attribution-NonCommercial-4.0 International License (CC BY-NC) (http://www.karger.com/Services/OpenAccessLicense). Usage and distribution for commercial purposes requires written permission.
spellingShingle Case Report
Rastrelli, Marco
Tropea, Saveria
Spina, Romina
Costa, Alessandra
Stramare, Roberto
Mocellin, Simone
Bonavina, Maria Giuseppina
Rossi, Carlo Riccardo
A Case of “en bloc” Excision of a Chest Wall Leiomyosarcoma and Closure of the Defect with Non-Cross-Linked Collagen Matrix (Egis(®))
title A Case of “en bloc” Excision of a Chest Wall Leiomyosarcoma and Closure of the Defect with Non-Cross-Linked Collagen Matrix (Egis(®))
title_full A Case of “en bloc” Excision of a Chest Wall Leiomyosarcoma and Closure of the Defect with Non-Cross-Linked Collagen Matrix (Egis(®))
title_fullStr A Case of “en bloc” Excision of a Chest Wall Leiomyosarcoma and Closure of the Defect with Non-Cross-Linked Collagen Matrix (Egis(®))
title_full_unstemmed A Case of “en bloc” Excision of a Chest Wall Leiomyosarcoma and Closure of the Defect with Non-Cross-Linked Collagen Matrix (Egis(®))
title_short A Case of “en bloc” Excision of a Chest Wall Leiomyosarcoma and Closure of the Defect with Non-Cross-Linked Collagen Matrix (Egis(®))
title_sort case of “en bloc” excision of a chest wall leiomyosarcoma and closure of the defect with non-cross-linked collagen matrix (egis(®))
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5118835/
https://www.ncbi.nlm.nih.gov/pubmed/27920698
http://dx.doi.org/10.1159/000452147
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