Paradoxical leanness in the imprinting-centre deletion mouse model for Prader–Willi syndrome

Prader–Willi syndrome (PWS), a neurodevelopmental disorder caused by loss of paternal gene expression from 15q11–q13, is characterised by growth retardation, hyperphagia and obesity. However, as single gene mutation mouse models for this condition display an incomplete spectrum of the PWS phenotype,...

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Detalles Bibliográficos
Autores principales: Golding, David M, Rees, Daniel J, Davies, Jennifer R, Relkovic, Dinko, Furby, Hannah V, Guschina, Irina A, Hopkins, Anna L, Davies, Jeffrey S, Resnick, James L, Isles, Anthony R, Wells, Timothy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bioscientifica Ltd 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5118940/
https://www.ncbi.nlm.nih.gov/pubmed/27799465
http://dx.doi.org/10.1530/JOE-16-0367

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