Cargando…

Hyperglycaemia-induced resistance to Docetaxel is negated by metformin: a role for IGFBP-2

The incidence of many common cancers varies between different populations and appears to be affected by a Western lifestyle. Highly proliferative malignant cells require sufficient levels of nutrients for their anabolic activity. Therefore, targeting genes and pathways involved in metabolic pathways...

Descripción completa

Detalles Bibliográficos
Autores principales:	Biernacka, K M, Persad, R A, Bahl, A, Gillatt, D, Holly, J M P, Perks, C M
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Bioscientifica Ltd 2016
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5118949/ https://www.ncbi.nlm.nih.gov/pubmed/27754854 http://dx.doi.org/10.1530/ERC-16-0095

Ejemplares similares

Insulin-like growth factor-binding protein-2 promotes prostate cancer cell growth via IGF-dependent or -independent mechanisms and reduces the efficacy of docetaxel
por: Uzoh, C C, et al.
Publicado: (2011)

IGF-1 and hyperglycaemia-induced FOXA1 and IGFBP-2 affect epithelial to mesenchymal transition in prostate epithelial cells
por: Mansor, Rehanna, et al.
Publicado: (2020)

A role for androgen receptor variant 7 in sensitivity to therapy: Involvement of IGFBP-2 and FOXA1
por: Biernacka, K.M., et al.
Publicado: (2023)

Correction: IGF-1 and hyperglycaemia-induced FOXA1 and IGFBP-2 affect epithelial to mesenchymal transition in prostate epithelial cells
por: Mansor, Rehanna, et al.
Publicado: (2023)

IGFBP-2 acts as a tumour suppressor and plays a role in determining chemosensitivity in bladder cancer cells
por: Tang, Zhen, et al.
Publicado: (2019)

Hypoxia negates hyperglycaemia-induced chemo-resistance in breast cancer cells: the role of insulin-like growth factor binding protein 2
por: Al Qahtani, Athba, et al.
Publicado: (2017)

Inhibition of FASN and ERα signalling during hyperglycaemia-induced matrix-specific EMT promotes breast cancer cell invasion via a caveolin-1-dependent mechanism
por: Zielinska, H.A., et al.
Publicado: (2018)

Interaction between GRP78 and IGFBP-3 Affects Tumourigenesis and Prognosis in Breast Cancer Patients
por: Zielinska, Hanna A., et al.
Publicado: (2020)

Editorial: The Role of the IGF/Insulin-IGFBP Axis in Normal Physiology and Disease
por: Takahashi, Shin-Ichiro, et al.
Publicado: (2022)

Are diet–prostate cancer associations mediated by the IGF axis? A cross-sectional analysis of diet, IGF-I and IGFBP-3 in healthy middle-aged men
por: Gunnell, D, et al.
Publicado: (2003)

Optimising the medical management of hyperglycaemia in type 2 diabetes in the Middle East: pivotal role of metformin
por: Al-Maatouq, M, et al.
Publicado: (2009)

Intrinsic, Pro-Apoptotic Effects of IGFBP-3 on Breast Cancer Cells are Reversible: Involvement of PKA, Rho, and Ceramide
por: Perks, Claire M., et al.
Publicado: (2011)

Metformin reduces insulin resistance and the tendency toward hyperglycaemia and dyslipidaemia in dogs with hyperadrenocorticism
por: Miceli, Diego Daniel, et al.
Publicado: (2018)

Metformin modulates hyperglycaemia-induced endothelial senescence and apoptosis through SIRT1
por: Arunachalam, Gnanapragasam, et al.
Publicado: (2014)

Metformin reduces airway glucose permeability and hyperglycaemia-induced Staphylococcus aureus load independently of effects on blood glucose
por: Garnett, James P, et al.
Publicado: (2013)

An In Vitro Study on the Combination Effect of Metformin and N-Acetyl Cysteine against Hyperglycaemia-Induced Cardiac Damage
por: Johnson, Rabia, et al.
Publicado: (2019)

Systemic Metabolism, Its Regulators, and Cancer: Past Mistakes and Future Potential
por: Holly, Jeff M. P., et al.
Publicado: (2019)

The Neglected Insulin: IGF-II, a Metabolic Regulator with Implications for Diabetes, Obesity, and Cancer
por: Holly, Jeff M. P., et al.
Publicado: (2019)

Hypoxia and hyperglycaemia determine why some endometrial tumours fail to respond to metformin
por: Sivalingam, Vanitha N., et al.
Publicado: (2019)

Epithelial-to-mesenchymal transition in breast cancer: a role for insulin-like growth factor I and insulin-like growth factor–binding protein 3?
por: Zielinska, Hanna A, et al.
Publicado: (2015)

Metformin prevents the effects of Pseudomonas aeruginosa on airway epithelial tight junctions and restricts hyperglycaemia‐induced bacterial growth
por: Patkee, Wishwanath R. A., et al.
Publicado: (2016)

Differential interactions between IGFBP-3 and transforming growth factor-beta (TGF-β) in normal vs cancerous breast epithelial cells
por: McCaig, C, et al.
Publicado: (2002)

Negative impact of hyperglycaemia on tocilizumab therapy in Covid-19 patients
por: Marfella, R., et al.
Publicado: (2020)

Prostate cancer - evidence of exercise and nutrition trial (PrEvENT): study protocol for a randomised controlled feasibility trial
por: Hackshaw-McGeagh, Lucy, et al.
Publicado: (2016)

Metformin promotes osteogenic differentiation and prevents hyperglycaemia-induced osteoporosis by suppressing PPARγ expression: Metformin prevents osteoporosis by suppressing PPARγ
por: Zheng, Lifeng, et al.
Publicado: (2023)

Galangin, a dietary flavonoid, ameliorates hyperglycaemia and lipid abnormalities in rats with streptozotocin-induced hyperglycaemia
por: Aloud, Amal A., et al.
Publicado: (2018)

Obesity, Diabetes and COVID-19: An Infectious Disease Spreading From the East Collides With the Consequences of an Unhealthy Western Lifestyle
por: Holly, Jeff M. P., et al.
Publicado: (2020)

Metformin stimulates IGFBP-2 gene expression through PPARalpha in diabetic states
por: Kang, Hye Suk, et al.
Publicado: (2016)

Glucocorticoid‐induced hyperglycaemia and diabetes: Call for action
por: Golubic, Rajna, et al.
Publicado: (2022)

Prostate cancer–Exercise and Metformin Trial (Pre-EMpT): study protocol for a feasibility factorial randomized controlled trial in men with localised or locally advanced prostate cancer
por: McGeagh, Lucy, et al.
Publicado: (2022)

Glucagon orchestrates stress‐induced hyperglycaemia
por: Harp, J. B., et al.
Publicado: (2016)

Steroid-induced hyperglycaemia in primary care
por: Mills, Edouard, et al.
Publicado: (2015)

Hyperglycaemia induced by isoniazid preventive therapy
por: Ganguly, Roshni Jhan, et al.
Publicado: (2018)

Hyperosmolar non-ketotic hyperglycaemia during oral diazoxide therapy of prolonged hyperglycaemia in infancy.
por: Savage, J. M., et al.
Publicado: (1977)

Practical Guide to Glucocorticoid Induced Hyperglycaemia and Diabetes
por: Barker, Hannah L., et al.
Publicado: (2023)

Dexamethasone-induced hyperglycaemia in COVID-19: Glycaemic profile in patients without diabetes and factors associated with hyperglycaemia
por: Rhou, Yoon Ji J, et al.
Publicado: (2022)

Hyperglycaemia, glycosuria and ketonuria may not be diabetes.
por: Gray, J., et al.
Publicado: (2003)

Hyperglycaemia-related occipital lobe seizures
por: Alakkas, A, et al.
Publicado: (2020)

Allithiamine Alleviates Hyperglycaemia-Induced Endothelial Dysfunction
por: Biró, Attila, et al.
Publicado: (2020)

Efficacy and tolerability of sitagliptin and metformin compared with insulin as an initial therapy for newly diagnosed diabetic patients with severe hyperglycaemia
por: He, Mingqian, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_rn3bj5tipbumi3dli9f5qmg3ke